Technology - BioXplor

Network Pharmacology is an emerging field based in systems pharmacology that looks at the effect of drugs on both the interactome and the diseasome. The drug-target network (DTN) can play an important role in understanding the mechanisms of action of approved and experimental drugs. With a network-based insight, network pharmacology intends to systematically reflect and reveal the biological foundation of complex diseases and drug effects. The unique network-based relationship that drug pairs with Complementary Exposure to the disease module tend to be effective drug combinations is consistent with the non-overlapping pharmacological principle in rational drug combination design (Yıldırım et al., Nature biotech (Nature biotechnology (119–1126), 2007).

Network Pharmacology